The Calm and Rebuild Pair (RCV PRO + NVC363) - Calmer, Stronger Skin

From Japan’s heritage rice fields to healthy, resilient skin.

In a 3-month clinical study involving 50 healthy volunteers, oral rice ceramide supplementation led to:

• Up to 47.1% reduction in transepidermal water loss (TEWL)
• Improved hydration, elasticity, and firmness across multiple skin areas
• Reduced wrinkle severity and less visible redness and pigmentation

Especially beneficial for individuals with compromised skin barriers, such as those experiencing eczema.

Why it matters: Skin ceramides are essential to barrier integrity. Supplementation restores the lipid matrix, sealing in moisture and shielding against environmental stressors.

Precision postbiotic with proven immune-calming effects.

Clinically validated to help reduce inflammatory markers linked to eczema:

• Significantly lowers IgE and histamine levels, easing itch and irritation
• Increases Treg and Th1 activity, while reducing Th2 and Th17 cytokines—key in calming hypersensitive skin responses
• Supports gut microbiota balance, which in turn supports immune harmony and skin clarity

Why it matters: LM1004’s heat-treated form preserves all the benefits of probiotics without the instability of live bacteria—making it potent, gentle, and cruelty-free. A smart choice for those looking to support their skin from the inside, naturally.

Clinically proven to defend your skin from inflammation and pigmentation.

A randomised, double-blind, placebo-controlled clinical trial showed that daily VIQUA® intake significantly:

• Reduced UV-induced erythema (redness) and melanin content
• Increased skin hydration and improved barrier function
• Delivered visibly brighter, more resilient skin over 8 weeks

Why it matters: UV and oxidative stress worsen eczema. VIQUA® helps neutralise these triggers with proven antioxidant and anti-inflammatory action.

Plant-Based Rebuilding: A Vegan Collagen Precursor.

VC-H1® is a plant-based glycoprotein, also known as Extensin, that is derived from plants.

Its structure mimics animal collagen, containing key amino acids like glycine and proline and the repeating GLY-X-Y tripeptide sequence that forms the smallest unit of collagen.

With an ultra-low molecular weight of 363 Daltons , it is easily absorbed and acts as a building block for the body to resynthesize its own collagen.

A preclinical study on skin demonstrated VC-H1®'s protective and rebuilding properties:

• Protects Existing Collagen: In the study, skin exposed to UVB radiation (the "UV group") saw its collagen content drop to ~65% of the normal level.
• Promotes Collagen Levels: The group supplemented with 1% VC-H1® was protected from this damage, maintaining collagen content at ~88%, which was nearly identical to the healthy, unexposed control group.
• Reduces Skin Damage: UVB exposure caused the epidermis (the skin's outer layer) to thicken by over 3x—a key sign of damage and photoaging.
• Improves Skin Structure: Supplementing with VC-H1® significantly reduced this damaging "thickening" effect, helping to maintain a healthier, more resilient skin structure.

Why it matters: In chronic conditions like eczema, the skin's primary issue is a compromised barrier. This barrier is what keeps moisture in and irritants or pathogens (like bacteria) out. Constant inflammation, dryness, and scratching severely damage this crucial structure.

This is where the "Rebuild" step is essential. The VC-H1 glycoprotein is a key component of the skin's dermal matrix. Its function is to provide structural integrity and help form a "barrier to bacterial infiltration" —a critical benefit for eczema-prone skin that is often susceptible to secondary infections. Furthermore, it is described as having an "excellent moisturizing effect" and the ability to "hold a large amount of moisture", directly addressing the persistent dryness that defines these conditions. While GliSODin works to "Calm" the internal inflammation, VC-H1 provides the essential, plant-based building blocks to help "Rebuild" a stronger, more resilient, and better-hydrated skin barrier.

The Antioxidant Catalyst: Clinically Proven to Calm and Protect.

GliSODin is a unique, patented form of the antioxidant enzyme Superoxide Dismutase (SOD) from French cantaloupe melon that is protected by a wheat protein (gliadin), allowing it to be orally effective. Unlike secondary antioxidants like vitamins, GliSODin is a primary antioxidant that works as a catalyst , promoting the body's own production of natural antioxidants.

Clinical studies on its effect on skin health have shown:

• Reduces Melasma: In a study on Indian patients with melasma, adding oral GliSODin to a standard Kligman's triple combination cream + sunscreen resulted in a 68% reduction in the Melasma Area and Severity Index (MASI) score, compared to only a 23% reduction for the group using the cream and sunscreen alone.
• Calms Redness (Erythema): Clinically shown to provide "Significant clinical benefits in the reduction of facial erythema (redness) and hyperpigmentation".
• Protects from UV Stress: Supports skin health against photo-oxidative stress (damage from sun exposure) and has been shown to reduce skin redness after UV exposure.
• Improves Skin Barrier: In a study alongside non-ablative fractional laser treatment, GliSODin "Improved the overall skin barrier and resulted in a greater brightening effect" compared to the control group.
• Supports Repigmentation (Vitiligo): A 24-week clinical study on patients with vitiligo found that the group taking GliSODin (GP-SOD) in combination with phototherapy (NB-UVB) showed a 19.85% improvement (repigmentation), which was more than double the improvement seen in the placebo + phototherapy group (8.83%).

Why it matters: Eczema and psoriasis are chronic inflammatory and immune-mediated conditions. This means the body's immune system is overactive, sending constant signals that create inflammation, redness, and irritation in the skin. The provided studies show GliSODin is a powerful immunomodulator that helps "Calm" this process.

It works by regulating your body's internal response system, helping to reduce pro-inflammatory cytokines (like TNF-alpha) —which are key drivers in psoriasis and eczema—while promoting anti-inflammatory cytokines (like IL-10). By calming this internal, chronic inflammation from the inside out, GliSODin directly addresses a root cause of flare-ups, helping to reduce the persistent redness (erythema) and sensitivity associated with these conditions.